Kay Schwarzkopf et.al.: Synthesis of novel optically active tin hydrides
containing chiral ligands
- Author(s): Kay Schwarzkopf, Juergen O. Metzger, Wolfgang Saak, Siegfried
Pohl
- Title: Synthesis of novel optically active tin hydrides containing
chiral ligands
- Date of Upload: 1997
- Article: Chemische
Berichte/Recueil (1997), 130(10), 1539-1546, Department of Chemistry,
University of Oldenburg, Carl-von-Ossietzky-Str. 9-11, 26129 Oldenburg,
Germany
- Keywords: chiral tin hydrides, chiral hydrogen donors, tin, ligand
effect, radical, reaction, selectivity, stereoselectivity, enetioselectivity
- Abstract:
- The synthesis of the chiral Sn bromides I (R = Br with R = tBu, R1 = Me,
R2 = H; R = tBu, R1 = H, R2 = Me; R = Ph, R1 = Me, R2 = H; R = Bu, R1 = tBu,
R2 = H; R = tBu, R1 = tBu, R2 = H) and the corresponding hydrides I (R = H),
contg. the potentially bidentate, optically active
2-[(1S/R)-1-(dimethylamino)ethyl]phenyl and
2-[(1S)-1-(dimethylamino)-2,2-dimethylpropyl]phenyl ligands, is reported. The
hydrides, with the Sn atom as the stereogenic center, were isolated as
diastereomeric mixts. with diastereomeric ratios of 50:50 to 80:20. The abs.
configuration of (-)-(1S)-1-(2-bromophenyl)-2,2-dimethylpropanamine was detd.
by single-crystal x-ray structure anal.
- URL: http://www.chemie.uni-oldenburg.de/oc/metzger/publikationen/pdf/75.pdf
(application/pdf)
This shadow-file was created by My Meta Maker
1.6.1. Last Update: Thu Jul 22 12:14:23 2004